Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Flow Cytometry

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all Common beta Chain Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Common beta Chain
Gly23-Trp443
Accession # P32927

Specificity

Detects human Common  beta  Chain in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human GM-CSF R alpha is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Common beta Chain Antibody [Biotin]

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Common  beta  Chain

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Common beta Chain

The common beta chain, also known as CD131, is a transmembrane protein that associates with the ligand-specific IL-3 R alpha, IL-5 R alpha, or GM-CSF R alpha proteins to form high affinity receptor complexes. beta c is expressed on a variety of hematopoietic cells.

Alternate Names

CD131, CSF2RB, GM-CSF R beta, IL-3 R beta, IL-5 R beta

Entrez Gene IDs

1439 (Human); 12983 (Mouse); 102143353 (Cynomolgus Monkey)

Gene Symbol

CSF2RB

UniProt

P32927

Additional Common beta Chain Products

Product Documents for Human Common beta Chain Antibody [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Common beta Chain Antibody [Biotin]

For research use only

Citations for Human Common beta Chain Antibody [Biotin]

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FAQs

No product specific FAQs exist for this product.

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Associated Pathways

Jak/STAT Signaling Pathway
Jak/STAT Signaling Pathway Thumbnail