Human FABP8/M-FABP Alexa Fluor® 750-conjugated Antibody

Catalog #: AF5866S Datasheet / COA / SDS

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AF5866S-100UG

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All FABP8/M-FABP Antibodies

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Human FABP8/M-FABP Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human FABP8 in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human (rh) FABP2, 3, 4, 5, 6, 7 and 9 is observed.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human FABP8
Ser2-Val132
Accession # P02689

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FABP8/M-FABP

FABP8 (fatty acid binding protein-8; also M [myelin]-FABP, P2 and PMP2) is a 15 kDa (predicted) member of the fatty acid binding protein family, calycin superfamily of molecules. It is found in Schwann cells, presumably on the cytoplasmic face of the plasma membrane where it may contribute to fatty acid transport across myelin. Functionally, FABP8 has a high affinity for U-shaped fatty acids such as oleic and palmitic acid. Human FABP8 is 132 amino acids (aa) in length and exhibits two layers of anti‑parallel beta -strands that envelope a hydrophobic pocket for lipid binding. Arg107 plus Arg127-Ile128-Tyr129 participate in fatty acid binding. Full length human FABP8 shares 87% and 95% aa identity with mouse and rabbit FABP8, respectively.

Long Name

Fatty Acid-Binding Protein 8

Entrez Gene IDs

5375 (Human); 18857 (Mouse); 688790 (Rat)

Alternate Names

FABP8; MFABP; M-FABP; MP2; myelin P2 protein; P2; peripheral myelin protein 2FABP8; PMP2