Human FXYD5/Dysadherin Alexa Fluor® 405-conjugated Antibody

Catalog #: AF8300V Datasheet / COA / SDS

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AF8300V-100UG

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Human FXYD5/Dysadherin Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human FXYD5/Dysadherin in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human FXYD5/Dysadherin
Gln22-Asp133
Accession # Q96DB9

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FXYD5/Dysadherin

Human FXYD5 (FXYD domain-containing ion transport regulator 5 and Dysadherin) is a 24 kDa glycoprotein and a member of the FXYD family of single span type I membrane proteins. This group of proteins has been shown to interact with the Na,K-ATPase and to modulate its properties. FXYD5 is structurally different from other family members and has been suggested to play a role in regulating E-cadherin and promoting metastasis. FXYD5 is preferentially expressed in kidney, intestine, spleen, stomach and lung. Human FXYD5 is 30% aa identical to mouse Fxyd5.

Long Name

FXYD Domain-containing Ion Transport Regulator 5

Entrez Gene IDs

53827 (Human); 18301 (Mouse)

Alternate Names

DYSAD; Dysadherin; EF-8; FXYD domain containing ion transport regulator 5; FXYD domain-containing ion transport regulator 5; FXYD5; IWU1; KCT1; keratinocytes associated transmembrane protein 1; OIT2; PRO6241; RIC