Human HOXB13 Alexa Fluor® 647-conjugated Antibody

Catalog #: AF8156R Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF8156R-100UG

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Human HOXB13 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human HOXB13 in direct ELISAs and Western blots.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived human HOXB13
Met1-Gln102
Accession # Q92826

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: HOXB13

HOXB13 (Homeobox B13) is a member of the homeobox family of transcription factors with a reported molecular weight of approximately 34 kDa. It is 284 amino acids in length and shares 93% aa identity with mouse and rat HOXB13. HOXB13 plays an important role in prostate cancer. Its expression promotes metastatis of prostate cancers and mutations in HOXB13 are associated with early onset disease. Elevated expression of HOXB13 is also associated with aggressive breast cancers, which may be due in part to its ability to reduce the expression of Estrogen Receptor alpha and increase expression of IL-6.

Long Name

Homeobox B13

Entrez Gene IDs

10481 (Human); 15408 (Mouse); 303480 (Rat)

Alternate Names

homeo box B13; homeobox B13; homeobox protein Hox-B13; HOXB13; PSGD