Human IFN-kappa Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB102471U Datasheet / COA / SDS

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FAB102471U-100UG

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All IFN-kappa Antibodies

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Human IFN-kappa Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human IFN‑ kappa in direct ELISAs.

Source

Monoclonal Mouse IgG2a Clone # 1009725

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human IFNâ€‘Îº
Leu28-Lys207
Accession # Q90W0

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IFN-kappa

Interferon kappa, also known as IFN-kappa, is a 207 aminoacids protein that in humans is encoded by the IFNK gene. IFN-kappa is a member of the type I interferon family which also includes IFN-alpha, -beta, -epsilon, and -omega. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. Human IFN-kappa has been detected in keratinocytes, monocytes, and monocyte-derived dendritic cells and is reported to have contact-dependent antiviral activity. Human papillomavirus (HPV) 16 oncogene expression, which is necessary for the development of cervical cancer, has been shown to down-regulate human IFN-kappa expression.

Long Name

Interferon kappa

Entrez Gene IDs

56832 (Human); 387510 (Mouse)

Alternate Names

IFNK; IFNkappa; IFN-kappa