Human MAP2 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB8304R Datasheet / COA / SDS

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FAB8304R-100UG

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Human MAP2 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human MAP2 in direct ELISAs.

Source

Monoclonal Mouse IgG3 Clone # 885232

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human MAP2
Gly1689-Lys1824
Accession # P11137

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MAP2

MAP2 (Microtubule-associated protein 2) is a 1827 amino acid (aa) cytoskeletal associated protein. Human MAP2 shares 84% and 79% aa identity with mouse and rat MAP2, respectively. Multiple splice forms exist, resulting in 4 distinct isoforms. MAP2 functions in microtubule polymerization and stabilization in both normal and malignant cell types. It has been demonstrated to play a critical role in neurite outgrowth and loss of MAP2 function in neurons may lead to neural degeneration.

Long Name

Microtubule-associated Protein 2

Entrez Gene IDs

4133 (Human); 17756 (Mouse)

Alternate Names

DKFZp686I2148; MAP2; MAP-2; MAP2A; MAP2B; MAP2C; Microtubule Associated Protein 2; microtubule-associated protein 2; MTAP2