Human Melusin Alexa Fluor® 405-conjugated Antibody

Catalog #: AF2740V Datasheet / COA / SDS

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AF2740V-100UG

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Human Melusin Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Melusin in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human Melusin
Ser2-Glu347
Accession # Q9UKP3

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Melusin

Melusin is a 38 kDa cytoplasmic protein that interacts specifically with the cytoplasmic domain of the beta 1 integrin subunit. It is expressed solely in striated muscle where it detects mechanical stress. The 347 amino acid residue human Melusin contains two amino terminal cysteine-rich repeats that are separated by an intervening sequence at the extreme carboxy-terminal. Melusin has a stretch of negatively charged residues (aspartic and glutamic acids). Human Melusin shares 93%, 92% and 96% amino acid sequence homology with rat, mouse and canine Melusin, respectively.

Entrez Gene IDs

26548 (Human)

Alternate Names

CHORDC3; integrin beta 1 binding protein (melusin) 2; integrin beta-1-binding protein 2; ITGB1BP; ITGB1BP2; Melusin; MGC119214