Human/Mouse PKA RII alpha Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB8000X Datasheet / COA / SDS

Recombinant Monoclonal Antibody

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FAB8000X-100UG

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Human/Mouse PKA RII alpha Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human PKA RII alpha in direct ELISAs. Detects human and mouse PKA RII alpha in Western blots.

Source

Monoclonal Rabbit IgG Clone # 2394D

Purification

Protein A or G purified

Immunogen

Synthetic peptide containing Human/Mouse PKA RIIÎ±
Accession # P13861

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PKA RII alpha

PRKAR2 is a regulatory subunit of the cAMP-dependent protein kinases involved in CAMP signaling in cells. Four types of regulatory chains are found and their expression varies among tissues. In some cases expression is constitutive and in other cases it is inducible. PRKAR2 seems to be involved in both endosome-to-Golgi and Golgi-to-ER transport.

Long Name

cAMP-dependent Protein Kinase Regulatory Type II alpha

Entrez Gene IDs

5576 (Human); 19087 (Mouse); 29699 (Rat)

Alternate Names

cAMP-dependent protein kinase regulatory subunit RII alpha; cAMP-dependent protein kinase type II-alpha regulatory subunit; PKA RII alpha; PKR2; PRKAR2; PRKAR2A; protein kinase A, RII-alpha subunit; protein kinase, cAMP-dependent, regulatory subunit type II alpha