Human MUC-19 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB8245R Datasheet / COA / SDS

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FAB8245R-100UG

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Human MUC-19 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human MUC-19 in direct ELISAs.

Source

Monoclonal Mouse IgG1 Clone # 876013

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human MUC-19
Lys5606-Gly5767
Accession # Q7Z5P9

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MUC-19

MUC-19 is a 6,254 amino acid member of the Mucin family of gel-forming glycoproteins. MUC-19 is expressed in corneal epithelial cells in the eye, conjuctival goblet and epithelial cells and lacrimal gland cells as well as by mucous cells of the submandibular gland and submucosal gland of the trachea. MUC-19 expression is reduced in patients with Sjogren syndrome (1,2). In a middle ear model of inflammatory response, MUC-19 is up-regulated in epithelial cells by exposure to cytokines including TNF-alpha, IL-1 beta, IL-5 and IL-8 (3).

Long Name

Mucin 19, Oligomeric

Entrez Gene IDs

283463 (Human)

Alternate Names

MUC19; MUC-19