Human PTGER1 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB10008G Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB10008G-100UG

Save 15% on Select RUO Reagents. See Details.

All PTGER1 Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PTGER1 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human PTGER1 in direct ELISAs.

Source

Monoclonal Mouse IgG1 Clone # 998412

Purification

Protein A or G purified

Immunogen

Synthetic peptide containing human PTGER1
Accession # P34995

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PTGER1

Prostaglandin E2 Receptor 1/ PTGER1/EP1, a member of the G protein-coupled receptor family, is one of four receptors for Prostaglandin E2 (PGE2). Expression is highest in kidney and spleen, with very low expression in most other tissues. Stimulation of angiogenesis in primate ovulatory follicles by luteinizing hormone has been shown to be mediated by PGE2 through PTGER1 and PTGER2 receptors. In epidermis, E2 plays a role in keratinocyte differentiaton. Expression and function of EP1 in carcinomas has been studied. For example, cytoplasmic and nuclear localization of EP1 in breast cancer has been reported in association with prognostic markers. And activation of EP1 mediated by COX2 causes VEGFC upregulation in lung adenocarcinomas.

Long Name

Prostaglandin E2 Receptor 1, Subtype EP1

Entrez Gene IDs

5731 (Human); 19216 (Mouse); 25637 (Rat)

Alternate Names

EP1; PGE receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1 (subtype EP1), 42kD; prostaglandin E receptor 1 (subtype EP1), 42kDa; prostaglandin E receptor 1, subtype EP1; prostaglandin E2 receptor EP1 subtype; Prostanoid EP1 receptor; PTGER1