Human PTGER3 Alexa Fluor® 750-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: PTGER3

Human Prostaglandin EP3 receptor, also known as EP3 or PTGER3, is a 53kDa prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER3 gene. PTGER3 is a G protein-coupled receptor (GPCR) of the rhodopsin-like receptor family. Along with several other receptor subtypes (EP1, EP2, and EP4), it mediates the diverse biological effects of Prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, induction of labor, cervical cancer, control of blood pressure, and asthma. Various isoforms are produced by alternative splicing. Prostaglandin E2 Receptor EP3 expression has been documented throughout the periphery, especially kidney. ESTs have been isolated primarily from kidney libraries.

Product Datasheets

Related Research Areas

• Bioactive Lipid G Protein-Coupled Receptors
• Bioactive Lipids and Receptors
• Eicosanoids and Regulators
• G Protein-Coupled Receptors in Immune Responses
• G Protein-Coupled Receptors in Obesity and Related Metabolic Disorders
• Obesity
• Platelet GPCRs
• Prostanoids and Receptors
• Steroid Hormones and Bioactive Lipids