Human PTP1B Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB1366X Datasheet / COA / SDS

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FAB1366X-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PTP1B Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human PTP1B in direct ELISAs.

Source

Monoclonal Mouse IgG2b Clone # 208607

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PTP1B
Glu2-Thr435
Accession # P18031

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PTP1B

Protein tyrosine phosphatase 1B (PTP1B) dephosphorylates tyrosine residues on several proteins including c-Src, beta-catenin, and the receptors for insulin and epidermal growth factor. PTP1B knock-out mice are resistant to high-caloric intake-induced obesity and have exaggerated insulin responses, suggesting that PTP1B may play a role in regulating growth factor responsiveness.

Long Name

Protein Tyrosine Phosphatase 1B

Entrez Gene IDs

5770 (Human); 19246 (Mouse)

Alternate Names

EC 3.1.3.48; protein tyrosine phosphatase 1B; protein tyrosine phosphatase, non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP1B; PTP-1B; PTP1Bprotein tyrosine phosphatase, placental; PTPN1; tyrosine-protein phosphatase non-receptor type 1