Human SRPK3 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB72301U Datasheet / COA / SDS

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FAB72301U-100UG

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Human SRPK3 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human SRPK3 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG1 Clone # 722516

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human SRPK3
Arg247-Ser316
Accession # Q9UPE1

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SRPK3

SRPK3 (Ser/Arg-rich protein specific kinase 3), also called MSSK-1 (muscle-specific serine kinase 1) or STK23 (Ser/Thr kinase 23) is a 59 kDa (predicted) cytoplasmic member of the CMGC Ser/Thr protein kinase family. SRPK3 is principally expressed in heart and skeletal muscle. SRPKs selectively phosphorylate Ser on RS domain-containing proteins, initiating mRNA splicing and maturation. The 533 amino acid (aa) human SRPK3 contains a split kinase domain (aa 79‑292 and 347‑531) separated by a hinge region. A 491 aa isoform shows an alternate translation start site at aa 43. Within the region used as an immunogen, human SRPK3 shares 87% and 86% aa identity with mouse and rat SRPK3, respectively.

Long Name

Ser/Arg-rich Protein-specific Kinase 3

Entrez Gene IDs

26576 (Human); 56504 (Mouse); 293854 (Rat)

Alternate Names

MGC102944; MSSK1; MSSK-1; MSSK1EC 2.7.11.1; Muscle-specific serine kinase 1; serine arginine rich protein-specific kinase 3; Serine/arginine-rich protein-specific kinase 3; serine/threonine kinase 23; Serine/threonine-protein kinase 23; serine/threonine-protein kinase SRPK3; SFRS protein kinase 3; SRPK3; SR-protein-specific kinase 3; SRSF protein kinase 3; STK23