Human Synaptopodin Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB8977N Datasheet / COA / SDS

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FAB8977N-100UG

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All Synaptopodin Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Synaptopodin Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Synaptopodin in direct ELISAs.

Source

Monoclonal Mouse IgG2a Clone # 918842

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Synaptopodin
Ser363-Gln490
Accession # Q8N3V7

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Synaptopodin

Synaptopodin is a 929 amino acid, actin associated protein with restricted expression in brain and kidney. First reported in glomerular podocytes, the protein is also found in postsynaptic densities (PSDs) in a subpopulation of telencephalic neurons where it is thought to participate in synaptic plasticity in dendritic spines. Despite its localization in PSDs, it is not homologous to other PSD proteins. Loss of synaptopodin expression has been demonstrated in Alzheimer’s patients. In glomeruli, synaptopodin localizes to the cytoplasm of podocyte foot processes.

Entrez Gene IDs

11346 (Human); 104027 (Mouse); 60324 (Rat)

Alternate Names

KIAA1029; Synaptopodin; SYNPO