Human VGLUT1/SLC17A7 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB9054N Datasheet / COA / SDS

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FAB9054N-100UG

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Human VGLUT1/SLC17A7 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human VGLUT/SLC17A7 in direct ELISAs.

Source

Monoclonal Mouse IgG2b Clone # 732607

Purification

Protein A or G purified

Immunogen

E.coli-derived recombinant human VGLUT/SLC17A7
Asn93-Thr115
Accession # Q9P2U7

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: VGLUT1/SLC17A7

Vesicular glutamate transporter 1 (VGLUT1), also known as SLC17A7, is an integral membrane protein involved in glutamate uptake into synaptic vesicles. The vesicular glutamate transporter (VGLUT) mediates the accumulation of neurotransmitter (glutamate) into synaptic vesicles. It is expressed in pre-synaptic vesicles. VGLUT proteins appear to be differentially expressed in myelinated afferents located in specific axonal populations within the spinal cord. VGLUT proteins are among the most specific markers for the identification of glutamatergic neurons. It is an essential molecular component of glutamate synaptic transmission, and its de-regulation can result synaptic failure and excitotoxicity.

Long Name

Vesicular Glutamate Transporter 1

Entrez Gene IDs

57030 (Human); 72961 (Mouse); 116638 (Rat)

Alternate Names

BNPI; BNPIbrain-specific Na-dependent inorganic phosphate cotransporter; Brain-specific Na(+)-dependent inorganic phosphate cotransporter; member 7; SLC17A7; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter); Solute carrier family 17 member 7; VGLUT1; VGLUT1vesicular glutamate transporter 1