LARGE Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-41323

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
View all LARGE1 Primary Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human LARGE (Uniprot#: O95461; Thr25-Ala178 (Uniprot#: O95461)

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for LARGE Antibody - BSA Free

LARGE Antibody

Western Blot: LARGE Antibody [NBP3-41323] -

Western Blot: LARGE Antibody [NBP3-41323] - Sample: Recombinant protein.
LARGE Antibody

Immunohistochemistry-Paraffin: LARGE Antibody [NBP3-41323] -

Immunohistochemistry-Paraffin: LARGE Antibody [NBP3-41323] - Used in DAB staining on fromalin fixed paraffin- embedded Kidney tissue

Applications for LARGE Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.05% Proclin 300

Concentration

0.66 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LARGE1

This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2018]

Long Name

xylosyl- and glucuronyltransferase LARGE1

Alternate Names

MDC1D, MDDGA6, MDDGB6

Gene Symbol

LARGE1

Additional LARGE1 Products

Product Documents for LARGE Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for LARGE Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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