LYK5 Antibody

Novus Biologicals | Catalog # NBP2-17187

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all LYK5 Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human LYK5. The exact sequence is proprietary.

Localization

Nucleus; Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LYK5 Antibody

Western Blot: LYK5 Antibody [NBP2-17187]

Western Blot: LYK5 Antibody [NBP2-17187]

Western Blot: LYK5 Antibody [NBP2-17187] - Sample (50 ug of whole cell lysate) A: mouse brain 12% SDS PAGE diluted at 1:1000
Immunohistochemistry-Paraffin: LYK5 Antibody [NBP2-17187]

Immunohistochemistry-Paraffin: LYK5 Antibody [NBP2-17187]

Immunohistochemistry-Paraffin: LYK5 Antibody [NBP2-17187] - Immunohistochemical analysis of paraffin-embedded Gastric ca, using antibody at 1:500 dilution.
Western Blot: LYK5 Antibody [NBP2-17187]

Western Blot: LYK5 Antibody [NBP2-17187]

Western Blot: LYK5 Antibody [NBP2-17187] - Sample (30 ug of whole cell lysate) A: 293T B: HepG2 12% SDS PAGE diluted at 1:1000
LYK5 Antibody

Immunocytochemistry/ Immunofluorescence: LYK5 Antibody [NBP2-17187] -

LYK5 antibody detects LYK5 protein at cytoplasm by immunofluorescent analysis.
Sample: MCF-7 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: LYK5 protein stained by LYK5 antibody (NBP2-17187) diluted at 1:500.
Blue: Hoechst 33342 staining.

Applications for LYK5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LYK5

The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq]

Alternate Names

LYK5FLJ90524, NY-BR-96, protein kinase LYK5, Serologically defined breast cancer antigen NY-BR-96, STE20-like pseudokinase, STE20-related adapter protein, STE20-related adaptor protein, STE20-related kinase adapter protein alpha, STE20-related kinase adaptor alpha, Stlk, STRAD alpha, STRADPMSE

Gene Symbol

STRADA

Additional LYK5 Products

Product Documents for LYK5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for LYK5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Protocols

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FAQs

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