Mkl1 Antibody (OTI3G7)

Novus Biologicals | Catalog # NBP2-45862

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3G7
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Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 165-397 of human MKL1(NP_065882) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Mkl1 Antibody (OTI3G7)

Western Blot: Mkl1 Antibody (OTI3G7) [NBP2-45862]

Western Blot: Mkl1 Antibody (OTI3G7) [NBP2-45862]

Western Blot: Mkl1 Antibody (3G7) [NBP2-45862] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Melan-A/MART-1.
Immunohistochemistry: Mkl1 Antibody (OTI3G7) [NBP2-45862]

Immunohistochemistry: Mkl1 Antibody (OTI3G7) [NBP2-45862]

Immunohistochemistry: Mkl1 Antibody (3G7) [NBP2-45862] - Analysis of Human Kidney tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Mkl1 Antibody (OTI3G7) [NBP2-45862]

Immunohistochemistry: Mkl1 Antibody (OTI3G7) [NBP2-45862]

Immunohistochemistry: Mkl1 Antibody (3G7) [NBP2-45862] - Analysis of Adenocarcinoma of Human breast tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

Applications for Mkl1 Antibody (OTI3G7)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Mkl1

MKL1 (megakaryoblastic leukemia 1 protein) was identified as part of a t(1;22) translocation with RBM15 associated with acute megakaryoblastic leukemia. It is a transcriptional coactivator of serum response factor (SRF) that promotes muscle differentiation and also plays a role in promoting maturation of megakaryocytes.

Long Name

Myocardin-related transcription factor A

Alternate Names

KIAA1438, MAL, MRTF-A, MRTFA

Gene Symbol

MRTFA

Additional Mkl1 Products

Product Documents for Mkl1 Antibody (OTI3G7)

Certificate of Analysis

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Product Specific Notices for Mkl1 Antibody (OTI3G7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Mkl1 Antibody (OTI3G7)

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Protocols

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