Monoglyceride Lipase Antibody

Novus Biologicals | Catalog # NBP1-89645

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Monoglyceride Lipase Antibody

Monoglyceride Lipase Antibody Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
Monoglyceride Lipase Antibody Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.
Monoglyceride Lipase Antibody Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Monoglyceride Lipase Antibody Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Immunohistochemistry: Monoglyceride Lipase Antibody [Monoglyceride Lipase Antibody]

Staining of human lung shows moderate cytoplasmic positivity in macrophages.

Applications for Monoglyceride Lipase Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Monoglyceride Lipase

Monoglyceride lipase (MGLL; EC 3.1.1.23) functions together with hormone-sensitive lipase (LIPE; MIM 151750) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL; MIM 238600) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides (Karlsson et al., 2001 [PubMed 11470505]).[supplied by OMIM]

Alternate Names

HUK5, MAGL, MGLL

Gene Symbol

MGLL

Additional Monoglyceride Lipase Products

Product Documents for Monoglyceride Lipase Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Monoglyceride Lipase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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