Mouse CD155/PVR Alexa Fluor® 488-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Examples

Flow Cytometry View Larger

Detection of CD155/PVR in Mouse Thymocytes by Flow Cytometry. Mouse thymocytes were stained with Rat Anti-Mouse CD155/PVR Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB6909G, filled histogram) or isotype control antibody (Catalog # IC006G, open histogram). View our protocol for Staining Membrane-associated Proteins.

Flow Cytometry View Larger

Detection of CD155/PVR in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD155/PVR Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB6909G, filled histogram) or isotype control antibody (Catalog # IC006G, open histogram). View our protocol for Staining Membrane-associated Proteins.

Preparation and Storage

Background: CD155/PVR

CD155, also known as PVR (Poliovirus Receptor) and Necl-5 (Nectin-like molecule-5), is a 70 kDa type I transmembrane glycoprotein that, in human, binds poliovirus as well as Vitronectin, Nectin-3, and DNAM-1. CD155 contains three Ig-like domains in its extracellular region. It is expressed in a variety of normal tissues and is upregulated in tumor cells of epithelial and neuronal origin. Within amino acids (aa) 29-348 of the extracellular region, mouse CD155 shares 45% and 73% aa sequence identity with human and rat CD155, respectively.

Product Datasheets

Related Research Areas

• Co-stimulatory and Co-inhibitory Molecules
• Infectious Diseases
• Monocyte Markers
• Nectin and Nectin-like Binding Receptors and Ligands
• Search Immune Checkpoint Targets