Mouse Epimorphin/Syntaxin 2 Antibody

Name: Mouse Epimorphin/Syntaxin 2 Antibody
Brand: R&D Systems
SKU: AF2568
Rating: 5 (1 reviews)

Catalog #: AF2568
1 Citation 1 Review Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF2568
AF2568-SP

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All Epimorphin/Syntaxin 2 Antibodies

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Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Epimorphin/Syntaxin 2 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Epimorphin/Syntaxin 2 in direct ELISAs and Western blots. In direct ELISAs, approximately 35% cross‑reactivity with recombinant human Epimorphin is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse Epimorphin/Syntaxin 2
Met1-Arg189
Accession # Q00262

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse Epimorphin/Syntaxin 2

Immunohistochemistry

5-15 µg/mL

Immersion fixed frozen sections of mouse embryo (E15)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Epimorphin/Syntaxin 2

Epimorphin, also known as syntaxin 2, is a member of the highly conserved syntaxin family. It is a type IV integral membrane protein with a C-terminal membrane anchor, and an N-terminal functional domain. Epimorphin can assume membrane topology with the functional domain localized extracellularly or to the cytoplasmic face. Extracellular Epimorphin functions in morphogenesis while intracellular syntaxin 2 functions as a vesicle fusion protein. Mouse Epimorphin functional domain shares 97% and 91% amino acid sequence homology with rat and human Epimorphin, respectively.

Entrez Gene IDs

2054 (Human); 13852 (Mouse)

Alternate Names

EPIMepimorphin; Epimorphin; EPM; STX2; STX2AMGC51014; STX2Bsyntaxin-2; STX2CEpimorphin; Syntaxin 2

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse Epimorphin/Syntaxin 2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Syntaxin-2 balances phagocytic uptake and phagolysosomal clearance in macrophages
Authors: Samanta, S;Nandi, A;Datta, R;Dolai, S;
Journal of cell science
Species: Mouse
Sample Types: Whole Cells
Applications: Immunocytochemistry