Mouse Intelectin‑2 Alexa Fluor™ Plus 594‑conjugated Antibody

R&D Systems | Catalog # FAB5358AFP594

R&D Systems

Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Western Blot

Label

Alexa Fluor Plus 594 (Excitation = 590 nm, Emission = 618 nm)

Antibody Source

Monoclonal Rat IgG1 Clone # 747421
View all Intelectin-2 Primary Antibodies »

Product Specifications

Specificity

Detects mouse Intelectin-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse (rm) Intelectin-1 is observed. In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) Intelectin-2 is observed, and approximately 15% cross-reactivity with rhIntelectin-1 is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Applications for Mouse Intelectin‑2 Alexa Fluor™ Plus 594‑conjugated Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Intelectin-2

Intelectin-2 (endothelial lectin 2; also ITLN-2 and HL-2) is a 40 kDa, likely Ca-dependent carbohydrate-binding lectin that is a member of the X-lectin family of molecules. It is secreted by intestinal Paneth cells and appears to participate in fungal microbe recognition. The Intelectin-2 precursor is 325 amino acids (aa) in length. It contains a 26 aa signal sequence and a 299 aa mature region. Although mouse Intelectin-2 is reportedly GPI-linked and mouse and human Intelectin-2 show considerable C‑terminal aa identity, it is not known if human Intelectin-2 is also GPI-linked. There is one fibrinogen-related domain in the mature molecule (aa 45‑210). One potential splice variant is reported that shows a premature truncation after Gly264. Over aa 20‑298, mouse Intelectin-2 shows 78% aa identity to human Intelectin-2.

Alternate Names

HL-2, Intelectin-b, Intelectin2, Itln1b, ITLN2, Itlnb

Entrez Gene IDs

142683 (Human); 493583 (Mouse)

Gene Symbol

ITLN2

UniProt

Q80ZA0

Additional Intelectin-2 Products

Product Documents for Mouse Intelectin‑2 Alexa Fluor™ Plus 594‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse Intelectin‑2 Alexa Fluor™ Plus 594‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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Protocols

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