Mouse NAC1 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB8375N Datasheet / COA / SDS

Recombinant Monoclonal Antibody

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FAB8375N-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse NAC1 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse NAC1 in direct ELISAs.

Source

Monoclonal Rabbit IgG Clone # 1243A

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant mouse NAC1
Val457-Gln514
Accession # Q7TS78

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: NAC1

NAC1 (Nucleus Accumbens-associated Protein 1) also known as NACC1, is a 527 amino acid (aa) BTB/POZ domain containing protein. Human NAC1 shares 86% and 85% aa sequence identity with mouse and rat NAC1, respectively. It has been shown to have a role in transcriptional regulation in both pluripotent stem cells and in the brain. Additionally, NAC1 expression is upregulated in many cancers and this expression has been suggested to correlate with increased aggressiveness in some cancers.

Long Name

Nucleus Accumbens Associated 1

Entrez Gene IDs

112939 (Human); 66830 (Mouse); 171454 (Rat)

Alternate Names

BEND8; BTB (POZ) domain containing 14B; BTB/POZ domain-containing protein 14B; BTBD14B; BTBD30; NAC1; NAC1BEN domain containing 8; NAC-1FLJ37383; NACC1; nucleus accumbens associated 1, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 1; transcriptional repressor NAC1