Mouse TORC1 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB5978V Datasheet / COA / SDS

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FAB5978V-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse TORC1 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse TORC1 in direct ELISAs.

Source

Monoclonal Rat IgG2a Clone # 505531

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant mouse TORC1
Gln384-Gln471
Accession # Q68ED7

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TORC1

TORC1, also known as CREB-regulated transcription coactivator 1 (crtc1), is a 67 kDa member of the TORC family. Mouse TORC1 is 630 amino acids (aa) in length. It contains multiple potential sites for phosphorylation and a serine-rich region from aa 295‑365. Mouse TORC1 is 97% and 90% aa identical to rat and human TORC1, respectively. TORC1 is highly expressed in specific regions of the brain including the cortex, hippocampus, and striatum. It functions as a transcription coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites.

Long Name

Transducer of Regulated CREB protein 1

Entrez Gene IDs

23373 (Human); 382056 (Mouse)

Alternate Names

CREB regulated transcription coactivator 1; CRTC1; FLJ14027WAMTP1; KIAA0616Transducer of regulated cAMP response element-binding protein 1; MECT1; MECT1CREB-regulated transcription coactivator 1; mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC1; TORC1TORC-1; Transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; WAMTP1