OSMR beta Antibody - IgG4SP, (Research Grade vixarelimab Biosimilar) - Low Endotoxin, Azide and BSA Free

Novus Biologicals | Catalog # NBP3-28875

Recombinant Monoclonal Antibody
Novus Biologicals

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG4 expressed in CHO

Format

Low Endotoxin, Azide and BSA Free
View all OSMR beta Primary Antibodies »

Product Specifications

Immunogen

OSMR

Clonality

Monoclonal

Host

Human

Isotype

IgG4

Description

The heavy chain type is huIgG4SP, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa.

Also known as 'vixarelimab'.

IgG4SP is human IgG4 with S228P mutation.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Scientific Data Images

OSMR beta Antibody (vixarelimab) - IgG4SP

Functional: OSMR beta Antibody (vixarelimab) - IgG4SP[NBP3-28875] -

OSMR beta Antibody (vixarelimab) - IgG4SP P-STAT3 Assay was evaluated using NHDF. The IC50 was approximately 0.3493 nM.
OSMR beta Antibody (vixarelimab) - IgG4SP

Functional: OSMR beta Antibody (vixarelimab) - IgG4SP[NBP3-28875] -

OSMR beta Antibody (vixarelimab) - IgG4SP MCP-1 secretion was evaluated using NHDF. The IC50 was approximately 0.0812 nM.
OSMR beta Antibody (vixarelimab) - IgG4SP

ELISA: OSMR beta Antibody (vixarelimab) - IgG4SP[NBP3-28875] -

Immobilized human OSMR His at 2 ug/mL can bind OSMR beta Antibody (vixarelimab) - IgG4SP, EC50=0.0024 ug/mL.
OSMR beta Antibody (vixarelimab) - IgG4SP

Flow Cytometry: OSMR beta Antibody (vixarelimab) - IgG4SP[NBP3-28875] -

Human OSMR HEK293 cells were stained with OSMR beta Antibody (vixarelimab) - IgG4SP and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.0359 ug/mL.

Applications

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry Panel Builder

Bio-Techne Knows Flow Cytometry

Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
Build Your Panel Now
Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Format

Low Endotoxin, Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: OSMR beta

Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF [provided by RefSeq]

Long Name

Oncostatin M Receptor beta

Alternate Names

OSM R beta, OSMR, OSMRB

Gene Symbol

OSMR

UniProt

Q99650

Additional OSMR beta Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews

There are currently no reviews for this product. Be the first to review OSMR beta Antibody - IgG4SP, (Research Grade vixarelimab Biosimilar) - Low Endotoxin, Azide and BSA Free and earn rewards!

Have you used OSMR beta Antibody - IgG4SP, (Research Grade vixarelimab Biosimilar) - Low Endotoxin, Azide and BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies