Phospho-Tau (T231) Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB34941S Datasheet / COA / SDS

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FAB34941S-100UG

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Phospho-Tau (T231) Alexa Fluor® 750-conjugated Antibody Summary

Specificity

Detects human Tau when phosphorylated at T231 in direct ELISAs.

Source

Monoclonal Mouse IgG1 Clone # 965319

Purification

Protein A or G purified

Immunogen

Phosphopeptide containing the human Tau T231 site
Accession # P10636

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Tau

Tau is a microtubule-associated protein primarily expressed in neurons. It can associate with microtubules through the carboxy-terminal domains and with the plasma membrane through the amino-terminal projection domain. Tau has a role as a stabilizer of microtubules. Abnormal Tau phosphorylation or splicing is associated with various neurological disorders.

Long Name

Microtubule-Associated Protein Tau

Entrez Gene IDs

4137 (Human); 17762 (Mouse); 29477 (Rat)

Alternate Names

DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPT; MGC138549; microtubule-associated protein tau; MSTD; MSTDMAPTL; MTBT1; MTBT1Neurofibrillary tangle protein; MTBT2; Neurofibrillary tangle protein; PHF-tau; PPND; Tau; TAUPaired helical filament-tau