Somatostatin Antibody (MSVA-638R)

Novus Biologicals | Catalog # NBP3-57261

Recombinant Monoclonal Antibody
Novus Biologicals

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # MSVA-638R
View all Somatostatin Primary Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human Somatostatin protein Swissprot P61278

Localization

Secreted

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody is highly specific and optimized for use in Immunohistochemistry.

It has been validated on TMAs covering 76 normal tissues and numerous cancer tissues.

The antibody concentration is optimized for dilution within dilution range using commercially available antibody diluent for immunohistochemistry.

Positive Control
Postive control:Pancreas: A subset of pancreatic islet cells should show strong somatostatin positivity..

Negative Control
Negitve control:Kidney: All cells must not show somatostatin immunostaining.

Storage
Antibody can be stored at 4degC. For extended storage, aliquot and store at -20degC. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Somatostatin Antibody (MSVA-638R)

Somatostatin Antibody (MSVA-638R)

Immunohistochemistry-Paraffin:Somatostatin Antibody (MSVA-638R)NBP3-57261

Pancreas Strong somatostatin positivity of a subset of pancreatic islet cells
Somatostatin Antibody (MSVA-638R)

Immunohistochemistry-Paraffin:Somatostatin Antibody (MSVA-638R)NBP3-57261

Duodenum mucosa Intense somatostatin staining of scattered neuroendocrine delta cells
Somatostatin Antibody (MSVA-638R)

Immunohistochemistry-Paraffin:Somatostatin Antibody (MSVA-638R)NBP3-57261

Esophagus Neuroendocrine carcinoma with strong somatostatin immunostaining of tumor cells

Applications for Somatostatin Antibody (MSVA-638R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100 1:200
Application Notes
Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer's directions.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS

Preservative

<0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Somatostatin

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. (provided by RefSeq)

Alternate Names

SMST, SOM, SRIF, SST

Gene Symbol

SST

Additional Somatostatin Products

Product Documents for Somatostatin Antibody (MSVA-638R)

Certificate of Analysis

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Product Specific Notices for Somatostatin Antibody (MSVA-638R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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