Tryptase alpha/beta 1 Antibody (SR1510) - BSA Free

Novus Biologicals | Catalog # NBP3-21686

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1510 expressed in HEK293

Format

BSA Free
View all Tryptase alpha/beta-1 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Tryptase alpha/beta 1 (Uniprot #: Q15661)

Specificity

Detects endogenous levels of Tryptase alpha/beta 1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Tryptase alpha/beta 1 Antibody (SR1510) - BSA Free

Immunohistochemistry: Tryptase alpha/beta 1 Antibody (SR1510) [NBP3-21686] -

Immunohistochemistry: Tryptase alpha/beta 1 Antibody (SR1510) [NBP3-21686] - Immunohistochemical analysis of paraffin-embedded human kidney, using NBP3-21686.

Western Blot: Tryptase alpha/beta 1 Antibody (SR1510) [NBP3-21686] -

Western Blot: Tryptase alpha/beta 1 Antibody (SR1510) [NBP3-21686] - Western blot analysis using NBP3-21686 in Human tonsil lysate.

Applications for Tryptase alpha/beta 1 Antibody (SR1510) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tryptase alpha/beta-1

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]

Alternate Names

TPS2, TPSB2, Tryptase beta-2, Tryptase beta2, Tryptase-C

Gene Symbol

TPSAB1

Additional Tryptase alpha/beta-1 Products

Product Documents for Tryptase alpha/beta 1 Antibody (SR1510) - BSA Free

Certificate of Analysis

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Product Specific Notices for Tryptase alpha/beta 1 Antibody (SR1510) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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