276 results for "Insulin R/CD220" in 产品
Insulin R/CD220 Products
Insulin Receptor (INSR, CD220) is a type I transmembrane glycoprotein in the Insulin/IGF Receptor family of receptor tyrosine kinases. The mature receptor contains an extracellular alpha subunit and an extracellular/transmembrane/cytoplasmic beta subunit. Alternative splicing generates A and B isoforms which may homodimerize or heterodimerize with the IGF-I receptor. All receptor combinations bind Insulin, IGF-I, or IGF-II, but with differing affinities. Insulin R signaling regulates glucose ...
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P06213-2 |
| Applications: | Binding Activity |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Flow, ICC/IF, CyTOF-ready |
B Isoform
| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | P06213.4 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #243522 |
| Applications: | Flow, ICC/IF |
| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | P15208 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #243524 |
| Applications: | Flow, ICC/IF |
| Reactivity: | Human |
| Assay Range: | 1250-80000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Applications: | ELISA |
High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
| Chemical Name: | 1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Porcine, Bovine, Sheep |
| Details: | Rabbit IgG Kappa Monoclonal Clone #83-14 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 1 More |
![Flow Cytometry: Insulin R/CD220 Antibody (83-14) - Chimeric - Azide and BSA Free [NBP2-81038]](https://resources.rndsystems.com/images/products/Insulin-R-CD220-Antibody-83-14-Flow-Cytometry-NBP2-81038-img0001.jpg "Flow Cytometry: Insulin R/CD220 Antibody (83-14) - Chimeric - Azide and BSA Free [NBP2-81038]")
Dual IR/IGF1R inhibitor
| Chemical Name: | 4-[[(2S)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-3-[7-methyl-5-(4-morpholinyl)-1H-benzimidazol-2-yl]-2(1H)-pyridinone |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #243523 |
| Applications: | WB |
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
| Chemical Name: | 2-[[2-[[1-[(Dimethylamino)ethanoyl]-5-(methyloxy)-2,3-dihydro-1H-indol-6-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-6-fluoro-N-methylbenzamide |
| Purity: | ≥98% |
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
| Alternate Names: | LDK378 |
| Chemical Name: | 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% |
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human |
| Applications: |
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
| Reactivity: | Mouse |
| Applications: |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |