Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
Select a category to see relevant filters and products
186 results for "CDK4" in 产品
CDK4 Products
Cyclin-dependent Kinase 4 (CDK4) is a 303 amino acid (aa) member of the Ser/Thr kinase family with a predicted molecular weight of 33.7 kDa. The human protein shares 94% and 95% aa sequence identity with the mouse and rat orthologs, respectively. CDK4 shuttles between the cytoplasm and nucleus as part of its role in cell cycle regulation. It promotes the transition from G1 to S phase by phosphorylating and inactivating RB1. Activation of CDK4 requires binding of a D-type Cyclin and ...
| Reactivity: | Human, Mouse, Rat, Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Simple Western |
Loading...
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #DCS-31 |
| Applications: | IHC, WB, ICC/IF, IP, MA |
Loading...
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF, Simple Western |
Loading...
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6N3M6 |
| Applications: | IHC, WB |
Loading...
| Alternate Names: | Gö 6850,Bisindolylmaleimide I |
| Chemical Name: | 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide |
| Purity: | ≥98% |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CDK4/7987R |
| Applications: | IHC |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL8102 |
| Applications: | IHC, WB, ICC/IF |
Loading...
| Alternate Names: | Palbociclib |
| Chemical Name: | 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one isethionate salt |
| Purity: | ≥98% |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #4F11 |
| Applications: | WB, ELISA, ICC/IF, Mycoplasma |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL8102 |
| Applications: | IHC, WB, ICC/IF |
Loading...
| Chemical Name: | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Purity: | ≥98% |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
Loading...
| Alternate Names: | L 86-8275 |
| Chemical Name: | 2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥98% |
Loading...
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2G7 |
| Applications: | WB, ELISA, ICC/IF |
Loading...
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #8A10 |
| Applications: | WB, ELISA, ICC/IF |
Loading...
| Alternate Names: | Mevinolin |
| Chemical Name: | (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate |
| Purity: | ≥97% |
Loading...
| Chemical Name: | (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate |
| Purity: | ≥98% |
Loading...
| Chemical Name: | 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione |
| Purity: | ≥98% |
Loading...
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #5-C3-G3-R |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Sensitivity: | 0.19 ng/mL |
| Assay Range: | 0.31 - 20 ng/mL |
| Applications: | ELISA |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CDK4/8351R |
| Applications: | IHC |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #CDK4/8351R |
| Applications: | IHC |
Loading...
| Chemical Name: | [4-Amino-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-5-pyrimidinyl](2,3-difluoro-6-methoxyphenyl)methanone |
| Purity: | ≥98% |
Loading...
| Chemical Name: | N-[4-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]butyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide |
| Purity: | ≥98% |
Loading...
| Alternate Names: | LEE-011 |
| Chemical Name: | 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide |
| Purity: | ≥98% |
Loading...