378 results for "Flt-3/Flk-2" in 产品

Flt-3/Flk-2 Products

The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.

Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Reactivity: Human
Applications:
Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)
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VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Alternate Names: Semaxinib
Chemical Name: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Purity: ≥98%
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
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Reactivity: Human
Details: Mouse IgG2b Lambda Monoclonal Clone #7E8.2C8
Applications: IHC, WB, Flow, ICC/IF, CyTOF-ready
Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)Azide and BSA Free [NBP2-80739]
(3)
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Reactivity: Human
Source: NS0
Accession #: AAA18947
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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Reactivity: Human
Details: Mouse IgG2b Lambda Monoclonal Clone #7E8.2C8
Applications: IHC, WB, Flow
Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)BSA Free [NBP2-42210]
(3)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF, Simple Western
Detection of Human Phospho-Flt-3/Flk-2 (Y591) antibody by Western Blot.
(3)
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Reactivity: Mouse
Details: Rat IgG2 Monoclonal Clone #12B6
Applications: IHC, WB
Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (12B6) - Azide and BSA Free [NB110-94155]
(2)
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Reactivity: Mouse
Source: NS0
Accession #: Q00342
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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Reactivity: Human
Source: HEK293
Accession #: P36888
Applications: Bioactivity
Recombinant Human Flt-3/Flk-2 His-tag Protein Binding Activity
(2)
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JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Alternate Names: CEP-701
Chemical Name: (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
Purity: ≥98%
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
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Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT

Chemical Name: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Purity: ≥98%
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #7B7C3
Applications: IHC, WB, ELISA
Western Blot: Flt-3/Flk-2/CD135 Antibody (7B7C3)BSA Free [NBP2-37363]
(4)
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Reactivity: Human
Assay Range: 125-8000 pg/mL
Applications: ELISA
Human Flt-3 / Flk-2 Ectodomain ELISA Standard Curve
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Reactivity: Human
Assay Range: 156-10000 pg/mL
Applications: ELISA
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Potent FLT3 inhibitor

Chemical Name: 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide
Purity: ≥98%
Potent FLT3 inhibitor
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Potent VEGFR, PDGFRβ and KIT inhibitor

Alternate Names: SU 11248
Chemical Name: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt
Purity: ≥98%
Potent VEGFR, PDGFRβ and KIT inhibitor
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Potent and selective PDGFR family inhibitor

Chemical Name: N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide
Purity: ≥98%
Potent and selective PDGFR family inhibitor
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