12 results for "GRIN2C/NMDAR2C Small Molecules and Peptides" in 产品

GRIN2C/NMDAR2C Small Molecules and Peptides

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, ...

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Non-competitive NMDA antagonist; acts at ion channel site

Alternate Names: Dizocilpine
Chemical Name: (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate
Purity: ≥98%
Non-competitive NMDA antagonist; acts at ion channel site
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Broad spectrum glutamatergic antagonist

Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid
Purity: ≥98%
Broad spectrum glutamatergic antagonist
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Highly potent NMDA antagonist

Chemical Name: trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline
Purity: ≥98%
Highly potent NMDA antagonist
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NMDA antagonist; acts at glycine site

Chemical Name: 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone
Purity: ≥98%
NMDA antagonist; acts at glycine site
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Potentiator of NMDA receptors containing GluN2C/GluN2D

Chemical Name: (3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone
Purity: ≥98%
Potentiator of NMDA receptors containing GluN2C/GluN2D
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Potent and selective NMDA antagonist

Chemical Name: (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid
Purity: ≥98%
Potent and selective NMDA antagonist
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Potent and selective NMDA antagonist; acts at the glycine site

Alternate Names: GV 150526A
Chemical Name: 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt
Purity: ≥98%
Potent and selective NMDA antagonist; acts at the glycine site
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GluN2C/GluN2D-selective NMDA antagonist

Chemical Name: (2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid
Purity: ≥98%
GluN2C/GluN2D-selective NMDA antagonist
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GluN2C/GluN2D-selective NMDA antagonist

Chemical Name: 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid
Purity: ≥97%
GluN2C/GluN2D-selective NMDA antagonist
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Potent and noncompetitive NMDA antagonist

Alternate Names: CNS 1102
Chemical Name: N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride
Purity: ≥98%
Potent and noncompetitive NMDA antagonist
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Non-competitive and GluN2C/GluN2D-selective NMDA antagonist

Chemical Name: 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)quinazolinyl]benzoic acid
Purity: ≥98%
Non-competitive and GluN2C/GluN2D-selective NMDA antagonist
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Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

Chemical Name: 4-Cyclohexyl-N-(7-hydroxy-5-methyl-2-propyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)benzenesulfonamide
Purity: ≥98%
Positive allosteric modulator of NMDA receptors; acts in transmembrane domain
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