234 results for "Lck" in 产品
Lck Products
Lck (p56lck) is a member of the Src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and over-expressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene. Lck behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show over-expression of Lck, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers.
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #755103 |
| Applications: | WB, ICC/IF |
Potent, selective Src family kinase inhibitor
| Chemical Name: | 3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #693010 |
| Applications: | WB, Flow, ICC/IF, Simple Western, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Lck Antibody [NBP1-85804]](https://resources.rndsystems.com/images/products/Lck-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-85804-img0005.jpg "Immunocytochemistry/ Immunofluorescence: Lck Antibody [NBP1-85804]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #755216 |
| Applications: | WB, ICC/IF |
Highly potent pan-Src/Bcr-Abl inhibitor
| Alternate Names: | BMS-354825 |
| Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #33D196 |
| Applications: | WB |
![Western Blot: Lck Antibody (33D196)BSA Free [NB100-56678]](https://resources.rndsystems.com/images/products/Lck-Antibody-33D196-Western-Blot-NB100-56678-img0001.jpg "Western Blot: Lck Antibody (33D196)BSA Free [NB100-56678]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #33D196 |
| Applications: | WB |
![Western Blot: Lck Antibody (33D196)Azide and BSA Free [NBP2-80832]](https://resources.rndsystems.com/images/products/Lck-Antibody-33D196-Azide-and-BSA-Free-Western-Blot-NBP2-80832-img0001.jpg "Western Blot: Lck Antibody (33D196)Azide and BSA Free [NBP2-80832]")
Dual site Src kinase inhibitor
| Chemical Name: | 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine |
| Purity: | ≥98% |
Potent and selective Lck and Src inhibitor; also inhibits SIK
| Alternate Names: | KIN112 |
| Chemical Name: | 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #355713 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_005356 |
| Applications: | Bioactivity |
| Reactivity: | Human, Mouse (Negative) |
| Details: | Mouse IgG1 Monoclonal Clone #LCK-01 |
| Applications: | WB, Flow, ICC/IF, IP, CyTOF-ready |
![Western Blot: Lck Antibody (LCK-01)BSA Free [NB500-336]](https://resources.rndsystems.com/images/products/p_2373_1.jpg "Western Blot: Lck Antibody (LCK-01)BSA Free [NB500-336]")
Potent Lck inhibitor
| Chemical Name: | 6-(2,6-Dimethylphenyl)-2-[[4-(4-methyl-1-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one |
| Purity: | ≥98% |
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
| Chemical Name: | 2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
| Purity: | ≥95% |
Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
| Alternate Names: | AZD 0530 |
| Chemical Name: | N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR2027 |
| Applications: | IHC, WB, Flow, ICC/IF, IP |
Potent and selective LCK Degrader (PROTAC®)
| Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-((6-(4-(3-(2-(4-(2,6-dioxopiperidin-3-yl)phenoxy)acetamido)propyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Lck [p Tyr394] Antibody [NBP3-13305]](https://resources.rndsystems.com/images/products/Lck-[p-Tyr394]-Antibody-Western-Blot-NBP3-13305-img0002.jpg "Western Blot: Lck [p Tyr394] Antibody [NBP3-13305]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |