272 results for "LRRK2" in 产品
LRRK2 Products
LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
LRRK2 antibodies are useful tools for neurodegeneration research and certian kinase signaling pathway studies.
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
| Alternate Names: | y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor |
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥98% |
Y-27632 synthesized to cGMP guidelines
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse, Bovine, C. elegans, Insect, +1 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, Flow, ICC/IF, + 1 More |
![Western Blot: LRRK2 AntibodyBSA Free [NB300-268]](https://resources.rndsystems.com/images/products/LRRK2-Antibody-Western-Blot-NB300-268-img0023.jpg "Western Blot: LRRK2 AntibodyBSA Free [NB300-268]")
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | KO, IHC, WB, Flow, ICC/IF, + 2 More |
![Knockout Validated: LRRK2 Antibody [NB110-58771]](https://resources.rndsystems.com/images/products/LRRK2-Antibody-Knockout-Validated-NB110-58771-img0009.jpg "Western Blot: LRRK2 Antibody [NB110-58771]")
| Reactivity: | Human, Mouse, Bovine, C. elegans, Human (Negative), +2 More |
| Applications: | KO, IHC, WB, Flow, ICC/IF, + 1 More |
![Immunohistochemistry-Frozen: LRRK2 Antibody Pack [NB100-938]](https://resources.rndsystems.com/images/products/LRRK2-Antibody-Pack-Immunohistochemistry-Frozen-NB100-938-img0017.jpg "Immunohistochemistry-Frozen: LRRK2 Antibody Pack [NB100-938]")
Protein kinase C inhibitor
| Alternate Names: | Gö 6850,Bisindolylmaleimide I |
| Chemical Name: | 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide |
| Purity: | ≥98% |
Protein kinase inhibitor
| Alternate Names: | SF 2370 |
| Chemical Name: | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester |
| Purity: | ≥98% |
| Reactivity: | Mouse, Human (Negative) |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: LRRK2 Antibody [NB110-55289]](https://resources.rndsystems.com/images/products/LRRK2-Antibody-Western-Blot-NB110-55289-img0006.jpg "Western Blot: LRRK2 Antibody [NB110-55289]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: LRRK2 Antibody - BSA Free [NBP1-78299]](https://resources.rndsystems.com/images/products/LRRK2-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-78299-img0002.jpg "Immunocytochemistry/ Immunofluorescence: LRRK2 Antibody - BSA Free [NBP1-78299]")
Potent and selective LRRK2 inhibitor
| Chemical Name: | rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole |
| Purity: | ≥98% |
Potent and selective LRRK2 inhibitor
| Chemical Name: | 5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% |
Potent, selective LRRK2 inhibitor; brain penetrant
| Chemical Name: | 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #521313 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: LRRK2 Antibody [NBP2-48524]](https://resources.rndsystems.com/images/products/LRRK2-Antibody-Western-Blot-NBP2-48524-img0004.jpg "Western Blot: LRRK2 Antibody [NBP2-48524]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #S138-6 |
| Applications: | WB, ICC/IF |
![Western Blot: LRRK2 Antibody (S138-6) [NBP2-42175]](https://resources.rndsystems.com/images/products/LRRK2-Antibody-S138-6-Western-Blot-NBP2-42175-img0003.jpg "Western Blot: LRRK2 Antibody (S138-6) [NBP2-42175]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1449 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #521309 |
| Applications: | ICC/IF |
Potent LRRK2 inhibitor
| Chemical Name: | N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide |
| Purity: | ≥98% |
Potent and selective LRRK2 inhibitor
| Chemical Name: | [4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone |
| Purity: | ≥98% |
| Reactivity: | Human |
| Applications: | AC |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1452 |
| Applications: | IHC, WB, ICC/IF, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #SR1451 |
| Applications: | IHC, WB, ICC/IF |
Sterile-filtered 10 mM solution of Y-27632, selective ROCK inhibitor, pre-dissolved in water
| Chemical Name: | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
| Purity: | ≥97% |
