8 results for "TrkB Small Molecules and Peptides" in 产品

TrkB Small Molecules and Peptides

Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization cons...

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Potent TrkB agonist

Chemical Name: N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
Purity: ≥98%
Potent TrkB agonist
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TrkB receptor antagonist

Chemical Name: N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide
Purity: ≥98%
TrkB receptor antagonist
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TrkB agonist

Alternate Names: 7,8-DHF
Chemical Name: 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
Purity: ≥98%
TrkB agonist
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Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Chemical Name: N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Purity: ≥98%
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
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TrkB receptor antagonist

Purity: ≥95%
TrkB receptor antagonist
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TrkB and TrkC agonist; brain penetrant

Chemical Name: 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
Purity: ≥97%
TrkB and TrkC agonist; brain penetrant
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Selective TrkB receptor agonist; neuroprotectant

Chemical Name: N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide
Purity: ≥98%
Selective TrkB receptor agonist; neuroprotectant
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Potent and selective pan-Trk inhibitor; peripherally restricted

Chemical Name: N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide
Purity: ≥98%
Potent and selective pan-Trk inhibitor; peripherally restricted
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