Bio-Techne Announces Travel Grants to ISSCR 2017

Euridice Ivette Lara Hinojosa, Student
Tlalpan, MEXICO

Mohammadali Sheikholeslam, Postdoctoral Fellow
Toronto, CANADA

Friederike Matheus, PhD Student
Munich, GERMANY

Ninuo Xia, Postdoctoral Fellow
Bozeman, MT, USA

Michalis Agathocleous, Assistant Instructor
Dallas, TX, USA
 
Stephanie Kennedy, Visiting Researcher
Los Angeles, CA, USA

Joyce van de Leemput, Assistant Project Scientist
San Diego, CA, USA

Louise Bundgaard, Postdoctoral Fellow
Copenhagen, DENMARK

Max Friesen, Graduate Student
Cambridge, MA, USA

Genny Filiciotto, PhD student
Manchester, UNITED KINGDOM

Terms and Conditions:

  1. Travel grants will be awarded to support attendance at ISSCR 2017 held in Boston, MA June 10-17, 2017 and no other event.
  2. All applications must be submitted to Bio-Techne via the online application between January 24, 2017 and March 28, 2017.
  3. Any researcher from an academic or non-profit institution is eligible to apply (technicians, PhD/graduate students, post-docs, principal investigators).
  4. Authorship on an abstract at ISSCR 2017 is not required.
  5. Applicants must complete the application form in full.
  6. Travel grants will not be awarded to employees of for-profit organizations (i.e. biotech or pharmacological companies).
  7. Travel grant recipients will be determined via a random drawing by Bio-Techne.
  8. The recipients will be contacted by email on April 7, 2017 and also announced online.
  9. Travel grants will be paid to the laboratory of the award recipient's principal investigator via the parent university or institution. If paid directly to the PI of the lab, taxes may apply.
  10. Proof of attendance at ISSCR 2017 will be required prior to travel grant payment.
  11. By submitting this application, you agree to receive information from Bio-Techne brands (R&D Systems, Tocris Bioscience and Novus Biologicals), including distributors. Your information will never be sold or used by a third party. See our complete Privacy Policy for more information.

Comments

Modeling aspects of bipolar disorder in neurons and astrocytes from patient-specific induced pluripotent stem cells

Jiang, Song, Corona, Kassem, Zheng, Detera-Wadleigh, McMahon

Human Genetics Branch, NIMH Intramural Research Program
NCATs

Lithium, valproic acid, gene expression, calcium imaging

Bipolar Disorder (BD) is a genetically heterogeneous psychiatric disorder of unknown etiology that presents major challenges for the study of disease biology and drug development. Induced pluripotent stem cells (iPSCs), which can be differentiated into neurons and glia, provide a cellular model system suitable for studies of cases and controls as well as studies that assess the impact of therapeutic agents on cellular development and differentiation. As part of the Amish-Mennonite Bipolar Genetics study (AMBiGen), we are collecting clinical data, DNA, and fibroblasts from probands diagnosed with BD and their relatives, all ascertained within genetically-isolated Amish and Mennonite communities in the Americas. Fibroblasts have been reprogrammed to iPSCs with Sendai virus and differentiated into neural progenitor cells (NPCs), neurons, and astrocytes using standard protocols. Pilot studies are underway in cells from 4 probands and 4 sex-matched, unaffected siblings (2 clones each). Assessments include morphology, action potentials, gene expression profiles, and cellular response to therapeutic dosages of established treatments such as lithium and valproic acid (VPA). Preliminary results suggest that long-term treatment with VPA, but not lithium, greatly reduced proliferation of NPCs by the MTT assay, and promoted neuronal differentiation in both cases and controls. Long-term treatment with lithium greatly reduced neuronal calcium response to glutamate stimulation in both cases and controls, based on single-cell calcium imaging. Interestingly, differentiation of NPCs into astrocytes was substantially slower and doubling time was shorter in cells derived from cases. VPA treatment (10 d at 1 mM) significantly reduced astrocyte growth in cells derived from both cases and controls, but the impact of VPA was substantially greater in case-derived cells. Lithium treatment (10 d at 1 mM) increased astrocyte density in lines derived from healthy controls, but not in lines derived from cases. These preliminary results, if replicated, could point to cell-autonomous phenotypes detectable in astrocytes derived from people diagnosed with BD. If astrocyte development is impaired in BD, this could have important implications for research into etiology and therapeutics.

I would like to attend the annual conference of ISSCR 2017. By attending the conference, I would get chance to expand my knowledge and interact with leading scientists of the world working in the Stem Cell research field. The grant will help to attend this conference.

Thanking you and with regards,

Sincerely,

Kameshwar P. Singh, D.V.M.; M.V.Sc.

Research Assistant Professor,

Environmental Medicine,

School of Medicine and Dentistry,

I will be very grateful if you help me to attend to the ISSCR annual meeting. I am from Mexico, and due to the lack of economical support and limited resouces we have as students is quite difficult to travel. By attending to the meeting, my research group and I will get the opportunity to talk out the results we have obtained, and get a feedback with others that are working in the same field. This is very valuable for me as a master student because I will get the opportunity to present a poster with the results we have obtained, and also to get the chance to interact with leading scientist of the world in the Stem Cell research field. 

Thank you, 

Sincerely, 

Biochemical Engineer Carmen Alejandra Morato Torres

UNAM, IFC

Mexico City

I work in the area of stem cell culture and media. I would like to attend the ISSCR 2017 meeting in Boston. Thank you.

Best regards,
Weiwei Liu