Potent purinergic agonist displaying selectivity for P2Y1
= 8.29 and 9.05 for P2Y1
= 19 nM for P2Y13
). Induces aggregation of, and inhibits cAMP accumulation in, platelets in vitro
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2-Methylthioadenosine[β-32P]diphosphate. An agonist and radioligand for the receptor that inhibits the accumulation of cyclic AMP in intact blood platelets.
Macfarlane et al.
A retrospective of recombinant P2Y receptor subtypes and their pharmacology.
Sak and Webb
P2Y13: identification and characterization of a novel Gαi-coupled ADP receptor from human and mouse.
Zhang et al.
The citations listed below are publications that use Tocris products. Selected citations for 2-Methylthioadenosine diphosphate trisodium salt include:
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