A 425619

   
Product Datasheet
Catalog Number:5781
Chemical Name:N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea
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Biological Activity
Potent TRPV1 antagonist (IC50 = 3-9 nM). Blocks capsaicin-evoked currents in rat DRG neurons and inhibits TRPV1-activation by anandamide (Cat. No. 1339) and N-arachidonoyl-dopamine. Reduces pain in inflammatory, postoperative and osteoarthritic in vivo pain models.
Technical Data
  • M.Wt:
    345.32
  • Formula:
    C18H14F3N3O
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    581809-67-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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