A2BP1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-90304

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all A2BP1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for A2BP1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: A2BP1 Antibody [NBP1-90304]

Immunocytochemistry/ Immunofluorescence: A2BP1 Antibody [NBP1-90304]

Immunocytochemistry/Immunofluorescence: A2BP1 Antibody [NBP1-90304] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus & cytosol.
A2BP1 Antibody - BSA Free Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Analysis in human cerebral cortex and pancreas tissues using NBP1-90304 antibody. Corresponding RBFOX1 RNA-seq data are presented for the same tissues.
A2BP1 Antibody - BSA Free Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Staining of human cerebral cortex shows strong nuclear positivity in neurons.
A2BP1 Antibody - BSA Free Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304]

Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304]

Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304] - Staining of human pancreas shows low expression as expected.
A2BP1 Antibody - BSA Free Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Staining of human tonsil shows no nuclear positivity in germinal center cells as expected.
A2BP1 Antibody - BSA Free Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Immunohistochemistry: A2BP1 Antibody - BSA Free [NBP1-90304]

Staining of human heart muscle shows weak nuclear and cytoplasmic positivity in cardiomyocytes.

Applications for A2BP1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: A2BP1

Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined. (provided by RefSeq)

Alternate Names

2BP1, A2BP, A2BP1 Hexaribonucleotide-binding protein 1, Ataxin-2-binding protein 1, FOX-1, FOX1 hexaribonucleotide binding protein 1, Fox-1 homolog A, HRNBP1 ataxin 2-binding protein 1, RNA binding protein fox-1 homolog 1, RNA binding protein, fox-1 homolog (C. elegans) 1

Gene Symbol

RBFOX1

Additional A2BP1 Products

Product Documents for A2BP1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for A2BP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for A2BP1 Antibody - BSA Free

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Protocols

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