ABCA4 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-47472

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all ABCA4 Primary Antibodies »

Product Specifications

Immunogen

ABCA4. (Uniprot# P78363)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

256 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ABCA4 Antibody - BSA Free

ABCA4 Antibody - BSA Free

Immunohistochemistry: ABCA4 Antibody - BSA Free [NBP3-47472] -

Immunohistochemistry: ABCA4 Antibody - BSA Free [NBP3-47472] - Immunohistochemistry of paraffin-embedded human colon cancer using (ABCA4 antibody) at dilution of 1:100

Applications for ABCA4 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:200

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ABCA4

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Alternate Names

ABC10, ABCRRMP, ARMD2DKFZp781N1972, ATP binding cassette transporter, ATP-binding cassette sub-family A member 4, ATP-binding cassette transporter, retinal-specific, ATP-binding cassette, sub-family A (ABC1), member 4, ATP-binding transporter, retina-specific, CORD3, EC 3.6.3, FFMFLJ17534, photoreceptor rim protein, retinal-specific ATP-binding cassette transporter, retina-specific ABC transporter, RIM ABC transporter, RIM protein, RmP, RP19, Stargardt disease protein, STGD, STGD1

Gene Symbol

ABCA4

Additional ABCA4 Products

Product Documents for ABCA4 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for ABCA4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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