Aiolos/IKZF3 Antibody (S01-0C5)

Name: Aiolos/IKZF3 Antibody (S01-0C5)
Brand: Novus Biologicals
SKU: NBP3-20069
Price: 559 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-20069

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-0C5 expressed in HEK293

View all Aiolos/IKZF3 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Aiolos/IKZF3 (Uniprot # Q9UKT9)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Aiolos/IKZF3 Antibody (S01-0C5)

Western Blot: Aiolos/IKZF3 Antibody (S01-0C5) [NBP3-20069]

Western Blot: Aiolos/IKZF3 Antibody (S01-0C5) [NBP3-20069] - Western blot detection of Aiolos/IKZF3 in HL-60, U251 cell lysates using NBP3-20069 (1:1000 diluted). Predicted band size: 58kDa. Observed band size: 58kDa.

Immunohistochemistry-Paraffin: Aiolos/IKZF3 Antibody (S01-0C5) [NBP3-20069]

Immunohistochemistry-Paraffin: Aiolos/IKZF3 Antibody (S01-0C5) [NBP3-20069] - Immunohistochemistry of Aiolos/IKZF3 in paraffin-embedded Human tonsil using NBP3-20069 at dilution 1/50

Applications for Aiolos/IKZF3 Antibody (S01-0C5)

Application

Recommended Usage

Immunohistochemistry

1/20

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Aiolos/IKZF3

IKZF3 encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq]

Long Name

DNA-binding Protein Aiolos

Alternate Names

AIO, IKZF3, ZNFN1A3

Gene Symbol

IKZF3

Additional Aiolos/IKZF3 Products

Product Documents for Aiolos/IKZF3 Antibody (S01-0C5)

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Certificate of Analysis

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Product Specific Notices for Aiolos/IKZF3 Antibody (S01-0C5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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