ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

Name: ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)
Brand: Novus Biologicals
SKU: NBP3-44502
Price: 589 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-44502

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Product Specifications
Scientific Data
Applications
Spectra Viewer
Flow Cytometry
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

ADC

Antibody Source

Monoclonal Human IgG₁

View all ALCAM/CD166 Primary Antibodies »

Product Specifications

Immunogen

ALCAM/CD166 (Uniprot: Q13740)

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Theoretical MW

145 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).

Praluzatamab Vedotin is an ADC consisting of an ALCAM-directed antibody and Monomethyl auristatin E (MMAE) used for the study of breast cancer.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

Flow Cytometry: Hu ALCAM/CD166 mAb [ADC] - (Praluzatamab Vedotin) [NBP3-44502]

Human ALCAM/CD166 HEK293 Cell Line were stained with ALCAM/CD166 and negative control protein respectively, washed and then followed by PE and analyzed with FACS, The EC50 is 0.61 ug/mL.

Applications for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Flow Cytometry Panel Builder

Bio-Techne Knows Flow Cytometry

Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

Build Your Panel Now

Formulation, Preparation, and Storage

Purification

> 90% by SDS-PAGE and HPLC

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: ALCAM/CD166

Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic andhomophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as ininteractions between cells of the nervous system

Long Name

Activated Leukocyte Cell Adhesion Molecule

Alternate Names

CD166

Additional ALCAM/CD166 Products

Product Documents for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

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Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.