ALK-1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-30982

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all ALK-1 Primary Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ALK-1. The exact sequence is proprietary.

Localization

Membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ALK-1 Antibody - BSA Free

Western Blot: ALK-1 Antibody [NBP1-30982]

Western Blot: ALK-1 Antibody [NBP1-30982]

Western Blot: ALK-1 Antibody [NBP1-30982] - Sample (20 ug of whole cell lysate) A: Hep G2 membrane extract 7. 5% SDS PAGE; antibody diluted at 1:5000.
Immunohistochemistry-Paraffin: ALK-1 Antibody [NBP1-30982]

Immunohistochemistry-Paraffin: ALK-1 Antibody [NBP1-30982]

Immunohistochemistry-Paraffin: ALK-1 Antibody [NBP1-30982] - Human heart, using Activin A Receptor Type II-like 1antibody(20 ug/ml). Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
Western Blot: ALK-1 Antibody [NBP1-30982]

Western Blot: ALK-1 Antibody [NBP1-30982]

Western Blot: ALK-1 Antibody [NBP1-30982] - Sample (30 ug of whole cell lysate) A: BCL-1 10% SDS PAGE; antibody diluted at 1:1000.

Applications for ALK-1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 20% Glycerol

Format

BSA Free

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALK-1

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Long Name

Activin Receptor-like Kinase 1

Alternate Names

ACVRL1, ALK1

Entrez Gene IDs

94 (Human); 11482 (Mouse)

Gene Symbol

ACVRL1

UniProt

P37023

Additional ALK-1 Products

Product Documents for ALK-1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for ALK-1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Citations for ALK-1 Antibody - BSA Free

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

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Associated Pathways

TGF-beta Signaling Pathways TGF-beta Signaling Pathway Thumbnail