AP3M1 Antibody

Name: AP3M1 Antibody
Brand: Novus Biologicals
SKU: NBP2-27068
Price: 319 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-27068

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Bovine, Canine, Chicken, Chinese Hamster, Equine

Predicted:

Monkey (100%), Mouse (100%), Opossum (100%), Orangutan (100%), Porcine (100%), Primate (100%), Rabbit (100%), Rat (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

The immunogen for this antibody was a portion of amino acid 140-190 of human AP3M1.

Reactivity Notes

The amino acid sequence used as immunogen for the AP3 antibody is 100% homologous in Macaque.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AP3M1 Antibody

Western Blot: AP3M1 Antibody [NBP2-27068]

Western Blot: AP3M1 Antibody [NBP2-27068] - Analysis of human Daudi lysate in the 1) absence and 2) presence of immunizing peptide probed with AP3 antibody at 4 ug/ml.

Immunohistochemistry-Paraffin: AP3M1 Antibody [NBP2-27068]

Immunohistochemistry-Paraffin: AP3M1 Antibody [NBP2-27068] - Formalin-fixed, paraffin-embedded human lung (respiratory epithelium) stained with AP3 antibody at 10 ug/ml.

Applications for AP3M1 Antibody

Application

Recommended Usage

Immunohistochemistry-Paraffin

10ug/ml

Western Blot

3-5ug/ml~

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AP3M1

Adaptor Protein 3 complex subunit mu-1 (AP3M1) belongs to the adaptor complexes medium subunit family and it contains one MHD (mu homology) domain. AP3 is a hetero-tetrameric protein complex composed of four subunits: two large (delta and beta3), one medium (mu3a/M1), and one small (sigma 3). Mutations in one of the large subunits of AP3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. It is also reported that AP3, is responsible for the trafficking of TLR9 to recognize viral nucleic acid. AP3 is also involved with a susceptibility gene for schizophrenia, dysbindin.

Alternate Names

adaptor-related protein complex 3, mu 1 subunit, AP-3 adapter complex mu3A subunit, MGC22164, mu-3A subunit, Mu3A-adaptin

Gene Symbol

AP3M1

UniProt

Q9Y2T2 (Human)

Additional AP3M1 Products

Product Documents for AP3M1 Antibody

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Certificate of Analysis

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Product Specific Notices for AP3M1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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