Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Western Blot, Immunoprecipitation

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all ARAP1 Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1160 and 1210 of human centaurin, delta 2 (ankyrin repeat, and pleckstrin homology domains-containing protein 1) using the numbering given in entry NP_056057.1 (GeneID 116985).

Reactivity Notes

Mouse reactivity reported in (PMID: 22573888).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARAP1 Antibody - BSA Free

Western Blot: ARAP1 Antibody [NB100-68223]

Western Blot: ARAP1 Antibody [NB100-68223]

Western Blot: ARAP1 Antibody [NB100-68223] - Detection of Human CENTD2/ARAP1 on HeLa whole cell lysate using NB100-68223. CENTD2/ARAP1 was also immunoprecipitated by another rabbit anti-CENTD2/ARAP1 antibody.

Applications for ARAP1 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
WB reactivity reported in (PMID: 22573888).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ARAP1

The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. The RHO-GAP activity may mediate cell rounding and loss of stress fibers. At least three transcript variants encoding different isoforms have been found for this gene, but the full-length natures of all variants have not been determined.

Alternate Names

arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1, centaurin, delta 2, Centaurin-delta-2, CENTD2ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containingprotein 1, cnt-d2, KIAA0782centaurin-delta-2

Entrez Gene IDs

116985 (Human)

Gene Symbol

ARAP1

UniProt

Q96P48 (Human)

Additional ARAP1 Products

Product Documents for ARAP1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for ARAP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for ARAP1 Antibody - BSA Free

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