Chemical Name: 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine
Biological ActivityAutophinib is a potent VPS34 inhibitor (IC50 = 19 nM). Inhibits starvation- and Rapamycin-induced autophagy (IC50 values = 40 and 90 nM, respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Identification and further development of potent TBK1 inhibitors.
Richters et al.
ACS Chem Biol., 2015;10:289
Phenotypic identification of a novel autophagy inhibitor chemotype targeting lipid kinase VPS34.
Robke et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Autophinib
There are currently no reviews for this product. Be the first to review Autophinib and earn rewards!
Have you used Autophinib?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image