B7-H6 Antibody

Novus Biologicals | Catalog # NBP1-91144

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all B7-H6 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TPLNDNVTIFCNIFYSQPLNITSMGITWFWKSLTFDKEVKVFEFFGDHQEAFRPGAIVSPWRLKSGDASLRLPGIQLEEAGEYRCEVVVTPLKAQGTVQLEVVASPASRLLLDQVGMKENEDKYMCESSGFY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for B7-H6 Antibody

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144] - Staining of human stomach shows weak to moderate membranous and cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144] - Staining of human breast cancer shows weak cytoplasmic positivity in tumor cells.
Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144] - Staining of human kidney shows weak membranous positivity in cells in glomeruli.
Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144]

Immunohistochemistry-Paraffin: B7-H6 Antibody [NBP1-91144] - Staining of human prostate shows weak to moderate cytoplasmic positivity in smooth muscle cells.

Applications for B7-H6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: B7-H6

B7-H6 is a transmembrane immune regulatory protein that binds to NKp30 expressed on NK cells. Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis. B7-H6 is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells. The expression of NKp30 ligands on tumor cells correlates with tumor cell sensitivity to NKp30-dependent cell lysis.

Long Name

B7 Homolog 6

Alternate Names

B7H6, DKFZp686I21167, DKFZp686O24166, NCR3LG1

Gene Symbol

NCR3LG1

Additional B7-H6 Products

Product Documents for B7-H6 Antibody

Certificate of Analysis

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Product Specific Notices for B7-H6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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