BAG2 Antibody

Novus Biologicals | Catalog # NB100-1776

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Porcine

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all BAG2 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence CSKTLQQNAESRFN corresponding to C-Terminus according to NP_004273.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for BAG2 Antibody

Western Blot: BAG2 Antibody [NB100-1776]

Western Blot: BAG2 Antibody [NB100-1776]

Western Blot: BAG2 Antibody [NB100-1776] - (0.3ug/ml) staining of Hela lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: BAG2 Antibody [NB100-1776]

Western Blot: BAG2 Antibody [NB100-1776]

Western Blot: BAG2 Antibody [NB100-1776] - staining of Pig Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for BAG2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

1:100-1:2000
Application Notes
WB: Approx. 25 kDa band observed in human HeLa lysates (calculated MW of 23.7 kDa band according to NP_004273.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BAG2

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Alternate Names

BAG family molecular chaperone regulator 2, BAG-2, BAG-family molecular chaperone regulator-2, Bcl-2-associated athanogene 2, BCL2-associated athanogene 2, dJ417I1.2, dJ417I1.2 (BAG-family molecular chaperone regulator 2), KIAA0576, MGC149462

Entrez Gene IDs

9532 (Human)

Gene Symbol

BAG2

UniProt

NP_004273.1 (Human)

Additional BAG2 Products

Product Documents for BAG2 Antibody

Certificate of Analysis

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Product Specific Notices for BAG2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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