BCOR Antibody

Novus Biologicals | Catalog # NB100-1280

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all BCOR Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence LSATPLYGNVHSW-C corresponding to N-Terminus according to NP_060215.4, NP_001116855.1, NP_001116856.1, NP_001116857.1.

Reactivity Notes

Expected from sequence similarity: Mouse, Dog, Pig, Cow

Specificity

This antibody is expected to recognise all reported isoforms. Variants (NP_060215.4; NP_001116855.1) encode the same isoform.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for BCOR Antibody

Immunofluorescence: BCOR Antibody [NB100-1280]

Immunofluorescence: BCOR Antibody [NB100-1280]

Immunofluorescence: BCOR Antibody [NB100-1280] - Analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).
Immunofluorescence: BCOR Antibody [NB100-1280]

Immunofluorescence: BCOR Antibody [NB100-1280]

Immunofluorescence: BCOR Antibody [NB100-1280] - Analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear and weak cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).

Applications for BCOR Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:28000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BCOR

BCOR is encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

ANOP2, BCL6 corepressor, BCL-6 corepressor, BCL6 co-repressor, BCL-6 interacting corepressor, BCoR, FLJ20285, FLJ38041, KIAA1575MGC71031, MAA2, MCOPS2, MGC131961

Entrez Gene IDs

54880 (Human); 71458 (Mouse)

Gene Symbol

BCOR

UniProt

NP_060215 (Human)

Additional BCOR Products

Product Documents for BCOR Antibody

Certificate of Analysis

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Product Specific Notices for BCOR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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