Beraprost sodium

Catalog # Availability Size / Price Qty
4180/1
Cat.No. 4180 - Beraprost sodium | C24H29NaO5 | CAS No. 88475-69-8
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Description: Potent prostacyclin IP receptor agonist

Chemical Name: 2,3,3a,8b-Tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-yn-1-yl)-1H-cyclopenta[b]benzofuran-5-butanoic acid sodium salt

Purity: ≥98%

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Biological Activity

Potent IP receptor agonist; analog of Epoprostenol (Cat. No. 2989). Potently inhibits ADP-induced platelet aggregation and P-selectin expression in vitro (pIC50 values are 8.26 and 8.56, respectively). Also increases vasodilation and reduces pulmonary hypertension in vivo. Orally active.

Technical Data

M.Wt:
420.47
Formula:
C24H29NaO5
Solubility:
Soluble to 25 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
88475-69-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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