Beraprost sodium

Tocris Bioscience | Catalog # 4180

Potent prostacyclin IP receptor agonist
Tocris Bioscience
Discontinued Product
4180 has been discontinued. View all Prostanoid Receptor Agonists products.

Key Product Details

Description

Potent prostacyclin IP receptor agonist
View all Prostanoid Receptor Agonists »

Product Description

Beraprost sodium is a potent IP receptor agonist; analog of Epoprostenol (Cat. No. 2989). Potently inhibits ADP-induced platelet aggregation and P-selectin expression in vitro (pIC50 values are 8.26 and 8.56, respectively). Also increases vasodilation and reduces pulmonary hypertension in vivo. Orally active.

Product Specifications for Beraprost sodium

Molecular Weight

420.47

Formula

C24H29NaO5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

rel-(1R,2R,3aS,8bS)-2,3,3a,8b-Tetrahydro-2-hydroxy-1-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl)-1H-cyclopenta[b]benzofuran-5-butanoic acid sodium salt

CAS Number

496807-11-5

PubChem ID

23663404

InChI Key

JLHRLDZCMGGIKW-OQNJEIHKSA-M

SMILES

O[C@@H]1C[C@H]2[C@H](C(C=CC=C3CCCC(O[Na])=O)=C3O2)[C@H]1/C=C/[C@@H](O)C(C)CC#CC.O[C@H]4C[C@@H]5[C@@H](C(C=CC=C6CCCC(O[Na])=O)=C6O5)[C@@H]4/C=C/[C@H](O)C(C)CC#CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 10.51 25

Preparing Stock Solutions for Beraprost sodium

The following data is based on the product molecular weight 420.47.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 9.51 mL 47.57 mL 95.13 mL
1.25 mM 1.90 mL 9.51 mL 19.03 mL
2.5 mM 0.95 mL 4.76 mL 9.51 mL
12.5 mM 0.19 mL 0.95 mL 1.90 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for Beraprost sodium

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Beraprost sodium

For research use only

Citations for Beraprost sodium

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